It is also obvious that the pH in topically applied preparations may play an important role.
It is therefore no surprise, that skin pH shifts have been observed in various skin pathologies. Chronic alkalization can throw this acid mantle out of balance, leading to inflammation, dermatitis, and atopic skin diseases. It is invisible to the eye but crucial to the overall wellbeing of skin. Reports on results of pH measurements from living skin established the term acid mantle – the skin’s own protective shield that maintains a naturally acid pH. The general usefulness of the pH concept for life science was recognized and later gained importance to analytical research. The concept of expressing acidity as the negative logarithm of the hydrogen ion concentration was defined and termed pH in the beginning of the 20th century.
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